Introduction to Bioinformatics, Biological Databanks,Biological Sequence Analysis: Genome-Microarray, pairwise sequence alignment, Dynamic programming, global and local alignment, Progressive multiple sequence alignment, Iterative multiple sequence alignment. BLAST Scoring matrices, gap penalty, statistical significance of multiple sequence alignment, sum-of-pairs method, CLUSTAL W, searching motifs in sequence alignment. Phylogentics – distance-based using UPGMA, Neighbour Joining. Protein Structure prediction – Secondary Structure prediction, Protein Secondry Structural Class prediction, Protein Fold recognition, Protein Tertiary Structure prediction. Protein-Protein Interaction, Protein Subcellular Localization, Emerging Areas in Bioinformatics.